The Enzyme Database

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EC 1.1.1.278     
Accepted name: 3β-hydroxy-5α-steroid dehydrogenase
Reaction: 3β-hydroxy-5α-pregnane-20-one + NADP+ = 5α-pregnan-3,20-dione + NADPH + H+
For diagram of reaction, click here
Systematic name: 3β-hydroxy-5α-steroid:NADP+ 3-oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 58875-02-8
References:
1.  Lindemann, P. and Luckner, M. Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata. Phytochemistry 46 (1997) 507–513.
2.  Warneck, H.M. and Seitz, H.U. 3β-Hydroxysteroid oxidoreductase in suspension cultures of Digitalis lanata EHRH. Z. Naturforsch. C: Biosci. 45 (1990) 963–972. [PMID: 2291772]
[EC 1.1.1.278 created 2003]
 
 


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