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Your query returned 1 entry. Printable version
EC | 1.1.1.262 | ||||||
Accepted name: | 4-hydroxythreonine-4-phosphate dehydrogenase | ||||||
Reaction: | 4-phosphooxy-L-threonine + NAD+ = 3-amino-2-oxopropyl phosphate + CO2 + NADH + H+ (overall reaction) (1a) 4-phosphooxy-L-threonine + NAD+ = (2S)-2-amino-3-oxo-4-phosphooxybutanoate + NADH + H+ (1b) (2S)-2-amino-3-oxo-4-phosphooxybutanoate = 3-amino-2-oxopropyl phosphate + CO2 (spontaneous) |
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For diagram of pyridoxal biosynthesis, click here | |||||||
Other name(s): | NAD+-dependent threonine 4-phosphate dehydrogenase; L-threonine 4-phosphate dehydrogenase; 4-(phosphohydroxy)-L-threonine dehydrogenase; PdxA; 4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase; 4-phosphonooxy-L-threonine:NAD+ oxidoreductase | ||||||
Systematic name: | 4-phosphooxy-L-threonine:NAD+ oxidoreductase | ||||||
Comments: | The product of the reaction undergoes decarboxylation to give 3-amino-2-oxopropyl phosphate. The enzyme is part of the biosynthesis pathway of the coenzyme pyridoxal 5′-phosphate found in anaerobic bacteria. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 230310-36-8 | ||||||
References: |
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