EC |
1.1.1.220 |
Accepted name: |
6-pyruvoyltetrahydropterin 2′-reductase |
Reaction: |
6-lactoyl-5,6,7,8-tetrahydropterin + NADP+ = 6-pyruvoyltetrahydropterin + NADPH + H+ |
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For diagram of 6-pyruvyltetrahydropterin metabolism, click here |
Other name(s): |
6-pyruvoyltetrahydropterin reductase; 6PPH4(2′-oxo) reductase; 6-pyruvoyl tetrahydropterin (2′-oxo)reductase; 6-pyruvoyl-tetrahydropterin 2′-reductase; pyruvoyl-tetrahydropterin reductase |
Systematic name: |
6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2′-oxidoreductase |
Comments: |
Not identical with EC 1.1.1.153 sepiapterin reductase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 97089-79-7 |
References: |
1. |
Milstien, S. and Kaufman, S. Biosynthesis of tetrahydrobiopterin: conversion of dihydroneopterin triphosphate to tetrahydropterin intermediates. Biochem. Biophys. Res. Commun. 128 (1985) 1099–1107. [DOI] [PMID: 4004850] |
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[EC 1.1.1.220 created 1989] |
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