| EC |
1.1.1.211 |
| Accepted name: |
long-chain-3-hydroxyacyl-CoA dehydrogenase |
| Reaction: |
(S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+ |
| Other name(s): |
β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD |
| Systematic name: |
long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase |
| Comments: |
Acts most rapidly on derivatives with chain-length 8 or 10 (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase). |
| Links to other databases: |
BRENDA, EXPASY, IUBMB, KEGG, CAS registry number: 84177-52-6 |
| References: |
| 1. |
El-Fakhri, M. and Middleton, B. The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria. Biochim. Biophys. Acta 713 (1982) 270–279. [PMID: 7150615] |
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| [EC 1.1.1.211 created 1986] |
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