| EC |
1.1.1.178 |
| Accepted name: |
3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
| Reaction: |
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD+ = 2-methylacetoacetyl-CoA + NADH + H+ |
| Other name(s): |
2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase; 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase; 2-methyl-3-hydroxy-butyryl CoA dehydrogenase |
| Systematic name: |
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase |
| Comments: |
Also acts, more slowly, on (2S,3S)-2-hydroxy-3-methylpentanoyl-CoA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 52227-66-4 |
| References: |
| 1. |
Conrad, R.S., Massey, L.K. and Sokatch, J.R. D- and L-isoleucine metabolism and regulation of their pathways in Pseudomonas putida. J. Bacteriol. 118 (1974) 103–111. [PMID: 4150713] |
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| [EC 1.1.1.178 created 1981] |
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