The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

[+subclass]. [+sub-subclass]. [+serial]

EC 1 [+]   
EC 2 [+]   
EC 3 [+]   
EC 4 [+]   
EC 5 [+]   
EC 6 []   
    EC 6.1  [+]      
    EC 6.2  [+]      
    EC 6.3  []      
        EC 6.3.1       [+]    Acid—ammonia (or amine) ligases (amide synthases) 
        EC 6.3.2       []    Acid—amino-acid ligases (peptide synthases) 
                EC 6.3.2.1                      pantoate—β-alanine ligase (AMP-forming) 
                EC 6.3.2.2                      glutamate—cysteine ligase 
                EC 6.3.2.3                      glutathione synthase 
                EC 6.3.2.4                      D-alanine—D-alanine ligase 
                EC 6.3.2.5                      phosphopantothenate—cysteine ligase (CTP) 
                EC 6.3.2.6                      phosphoribosylaminoimidazolesuccinocarboxamide synthase 
                EC 6.3.2.7                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—L-lysine ligase 
                EC 6.3.2.8                      UDP-N-acetylmuramate—L-alanine ligase 
                EC 6.3.2.9                      UDP-N-acetylmuramoyl-L-alanine—D-glutamate ligase 
                EC 6.3.2.10                      UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase 
                EC 6.3.2.11                      carnosine synthase 
                EC 6.3.2.12                      dihydrofolate synthase 
                EC 6.3.2.13                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase 
                EC 6.3.2.14                      enterobactin synthase 
                EC 6.3.2.15                       UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase. The activity observed is due to EC 6.3.2.10, UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase 
                EC 6.3.2.16                      D-alanine—alanyl-poly(glycerolphosphate) ligase 
                EC 6.3.2.17                      tetrahydrofolate synthase 
                EC 6.3.2.18                      γ-glutamylhistamine synthase 
                EC 6.3.2.19                      ubiquitin—protein ligase. The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with EC 6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of EC 2.3.2.23 (E2 ubiquitin-conjugating enzyme) and EC 2.3.2.27 (RING-type E3 ubiquitin transferase) 
                EC 6.3.2.20                      indoleacetate—lysine synthetase 
                EC 6.3.2.21                      ubiquitin—calmodulin ligase. The reaction is performed by the sequential action of EC 6.2.1.45 (ubiquitin-activating enzyme E1), several ubiquitin transferases and finally by EC 2.3.2.27 [ubiquitin transferase RING E3 (calmodulin-selective)] 
                EC 6.3.2.22                      diphthine—ammonia ligase. Now EC 6.3.1.14, diphthine—ammonia ligase. 
                EC 6.3.2.23                      homoglutathione synthase 
                EC 6.3.2.24                      tyrosine—arginine ligase 
                EC 6.3.2.25                      tubulin—tyrosine ligase 
                EC 6.3.2.26                      N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase 
                EC 6.3.2.27                      The activity is covered by two independent enzymes, EC 6.3.2.38 N2-citryl-N6-acetyl-N6-hydroxylysine synthase, and EC 6.3.2.39, aerobactin synthase 
                EC 6.3.2.28                      L-amino-acid α-ligase. Now EC 6.3.2.49, L-alanine-L-anticapsin ligase 
                EC 6.3.2.29                      cyanophycin synthase (L-aspartate-adding) 
                EC 6.3.2.30                      cyanophycin synthase (L-arginine-adding) 
                EC 6.3.2.31                      coenzyme F420-0:L-glutamate ligase 
                EC 6.3.2.32                      coenzyme γ-F420-2:α-L-glutamate ligase 
                EC 6.3.2.33                      tetrahydrosarcinapterin synthase 
                EC 6.3.2.34                      coenzyme F420-1:γ-L-glutamate ligase 
                EC 6.3.2.35                      D-alanine—D-serine ligase 
                EC 6.3.2.36                      4-phosphopantoate—β-alanine ligase 
                EC 6.3.2.37                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine ligase 
                EC 6.3.2.38                      N2-citryl-N6-acetyl-N6-hydroxylysine synthase 
                EC 6.3.2.39                      aerobactin synthase 
                EC 6.3.2.40                      cyclopeptine synthase 
                EC 6.3.2.41                      N-acetylaspartylglutamate synthase 
                EC 6.3.2.42                      N-acetylaspartylglutamylglutamate synthase 
                EC 6.3.2.43                      [amino-group carrier protein]—L-2-aminoadipate ligase 
                EC 6.3.2.44                      pantoate—β-alanine ligase (ADP-forming) 
                EC 6.3.2.45                      UDP-N-acetylmuramate—L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioate ligase 
                EC 6.3.2.46                      fumarate—(S)-2,3-diaminopropanoate ligase 
                EC 6.3.2.47                      dapdiamide synthase 
                EC 6.3.2.48                      L-arginine-specific L-amino acid ligase 
                EC 6.3.2.49                      L-alanine—L-anticapsin ligase 
                EC 6.3.2.50                      tenuazonic acid synthetase 
                EC 6.3.2.51                      phosphopantothenate—cysteine ligase (ATP) 
                EC 6.3.2.52                      jasmonoyl—L-amino acid ligase 
                EC 6.3.2.53                      UDP-N-acetylmuramoyl-L-alanine—L-glutamate ligase 
                EC 6.3.2.54                      L-2,3-diaminopropanoate—citrate ligase 
                EC 6.3.2.55                      2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase 
                EC 6.3.2.56                      staphyloferrin B synthase 
                EC 6.3.2.57                      staphyloferrin A synthase 
                EC 6.3.2.58                      D-ornithine—citrate ligase 
                EC 6.3.2.59                      3-methyl-D-ornithine—L-lysine ligase 
                EC 6.3.2.60                      glutamate—[amino group carrier protein] ligase 
                EC 6.3.2.61                      tubulin-glutamate ligase 
                EC 6.3.2.62                      β-tubulin-glutamate ligase 
        EC 6.3.3       [+]    Cyclo-ligases 
        EC 6.3.4       [+]    Other carbon-nitrogen ligases 
        EC 6.3.5       [+]    Carbon-nitrogen ligases with glutamine as amido-N-donor 
    EC 6.4  [+]      
    EC 6.5  [+]      
    EC 6.6  [+]      
    EC 6.7  [+]      
EC 7 [+]   


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